Sustained pacemaker function is a challenge in biological pacemaker engineering.Human cardiomyocyte progenitor cells (CMPCs) have exhibited extended survival in the heart after transplantation.We studied whether lentivirally transduced CMPCs that express the pacemaker current If (encoded by HCN4) can be used as functional gene delivery vehicle in b
Forest canopies contribute significantly to global forest biodiversity and ecosystem functioning, yet are declining and understudied.One reason for a knowledge gap is that accessing forest canopies can be difficult and dangerous.Thus, lack of relevant canopy access skills may compromise knowledge gain and personal safety.We assessed skill levels in
Campylobacter jejuni is the causal agent of the food-borne infection with the highest incidence in Europe.Both poultry and wild birds are a major reservoir.To gain insight into the population structure, virulence potential, and antimicrobial resistance (AMR), a collection of 150 isolates from three different Beer Glass ecological niches (broilers,
During embryogenesis motor axons navigate to their target muscles, where individual motor axons develop complex branch morphologies.The mechanisms that control axonal branching morphogenesis have been studied intensively, yet it still remains unclear when branches begin to form or how branch locations are determined.Live cell imaging of individual
Applying biochar to soil is thought to have multiple benefits, from helping mitigate climate change [ 1 , 2 Necklaces ], to managing waste [ 3 ] to conserving soil [ 4 ].Biochar is also widely assumed to boost crop yield [ 5 , 6 ], but there is controversy regarding the extent and cause of any yield benefit [ 7 ].Here we use a global-scale meta-ana